Although the available limited evidence suggested a protective role of APN on ovarian carcinogenesis, additional studies are necessary to elucidate its function in ovarian tumor onset and progression. Low APN blood levels were also associated with an increased risk and a worse prognosis of endometrial cancer. Additionally, a low expression of AdipoR1 in endometrial cancer cells is associated with advanced...
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Before delving into the content of this essay, it is crucial to understand why this argument is valid. Cancer is a fatal disease and the chances of survival, especially for skin cancer, vary greatly depending on how early and accurately it is diagnosed (The Skin Cancer Foundation, 2019). Recognising cancerous cells from benign ones requires not only medical knowledge but...
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Abstractâ Image processing techniques are widely used in several medical problems for image enhancement in the detection phase to support early medical treatment. In this research, we aim to improve quality and accuracy of early detection of lung cancer through a combination of image processing techniques and machine learning. The Cancer Imaging Archive (TCIA) dataset has been used for training...
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Abstract: Lung cancer is one of the most serious cancers in the world, with the smallest survival rate after the diagnosis. In CT scans, lung nodules appear as dense masses of various shapes and sizes. They may be isolated from or attached to other structures such as blood vessels or the pleura. In this paper a detection of Candidate Nodules...
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Abstract: Lung cancer is one of the most increasing diseases in the rapidly changing world. This disease can be cured in the initial stage. It should be identified at the early stage for diagnosis purposes. The prediction of lung disease stages can be done using image processing techniques. The proposed algorithm consists of a segmentation process using Dual-Tree Complex Wavelet...
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Abstract Female non-smokers face a much higher risk of death from lung cancer over the last few years. Many causes explain why lung cancer rates have skyrocketed among the women non-smokers. The increase in mortality risk from lung cancer in female never-smokers can be due to causes including environmental tobacco smoke, radon(a radioactive gas found in nature in soil and...
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1. Introduction. With cancer affecting 1 in 7 men in South Africa (SA) during their lifetime prostate cancer (PCa) is the no. 1 cancer that affects SA men, It is estimated that 1 in 18 SA men will develop prostate cancer according to the National Cancer Registry of South Africa. (NCR-SA, 2014).â Prostatic adenocarcinoma (typically called âprostate cancerâ or âprostate...
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Introduction Lung cancer remains a leading cause of cancer-related mortality worldwide, primarily due to late-stage diagnosis. The early detection of lung nodules, which can be precursors to malignant tumors, is crucial for improving patient outcomes. Convolutional Neural Networks (CNNs), a subclass of deep learning models, have emerged as formidable tools in medical imaging for their ability to automate and enhance...
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Abstractâ Breast Cancer is one of the most common disease that is responsible for a high number of deaths every year. Despite the fact that cancer is treatable and healable in earliest stages, A huge number of patients are examined with cancer very late. Data mining process and classification are efficient way to categorise the data particularly in medical fields,...
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Analysis towards Melanoma Abstractâ Melanoma is only harmful in human epidemic diseases and the level of these diseases is increasing continuously. Computers are not more intelligent than humans, but it is easy to find some information easily, which may not be easily apparent to the human eye. Such as: skin color variations or taxa variations. As knowledge is in inadequate...
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Introduction: Melanoma and non-melanoma skin cancer are the most common type of malignancy in the Caucasian population (1-10). The incidence of both MM and NMSC is on the rise ,with an annual increase in MM of 0.6% among adults over 50 years (11). The incidence of melanoma may be even higher than indicated, as the national cancer registries has reported...
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Introduction Prostate cancer is one of the most prevalent malignancies affecting men worldwide, with significant implications for morbidity and mortality. Radiotherapy remains a cornerstone in the management of prostate cancer, offering a potentially curative treatment modality. However, the precision of radiotherapy planning is crucial to maximize therapeutic efficacy while minimizing damage to surrounding healthy tissues. Positron Emission Tomography (PET) imaging...
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Abstractâ Skin lesions are significant in determining dermatological medical conditions globally. Early diagnosis of malignant melanoma by dermoscopy imaging considerably will increase the survival rate. Throughout this paper, we tend to present deep learning-based approaches to resolve 2 issues in skin lesion analysis employing a dermoscopic image containing the tumor. Estimation of these biomarkers are wont to give some insight,...
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Introduction High treatment costs, strenuous treatment plans, and emotional stress on the patient and on her family are the burdens women with breast cancer have to handle. Breast cancer is the most prevalent cancer among women in the US with 245,299 new cases and 41,487 deaths as a result in 2016 with higher rates present in both cottonwood county and...
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Introduction The advancements in NGS technologies and the emergence of Omics field has led to the development of various approaches in studying cancer. The common approaches to identify molecular mechanisms in cancer include scanning the genome for cancer-specific mutations, exploring differential expression of mRNA through transcriptomics or that of protein through proteomics [Chakraborty S et al. (2018)]. However, limiting the...
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Introduction Ovarian cancer (OC) is the 9th most common cancer and the 9th most common cause of cancer-related death in women, with an overall 5-year survival of approximately 40%. In 2018, 295,414 new cases of OC were documented worldwide, 184,799 of which resulted in death (1). High-grade serous ovarian carcinoma (HGSOC) is the most common and deadliest subtype of epithelial...
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Introduction Prostate cancer is the second most frequently diagnosed cancer in the world.1 Androgen deprivation therapy is the main treatment for advanced disease. Androgen deprivation therapy (ADT) is a temporary measure but can accelerate osteoporosis, and bone metastases are common in advanced prostate cancer and are associated with significant morbidity, including pain. All patients eventually develop castration-resistant prostate cancer (CRPC)....
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Introduction Drug discovery and development involve a number of stages to develop a novel drug, therefore a reduction in time frame new approach is developed which is repurposing of existing drugs. Till to date, the importance of drug repurposing is significantly increased to identify new use of the pre-existing drug. Repurposed of the drug can be achieved by two methods,...
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Introduction Cancer remains one of the leading causes of morbidity and mortality worldwide, prompting extensive research into preventive measures. The relevance of diet and lifestyle in cancer prevention has gained considerable attention, with studies suggesting that up to 30-50% of cancer cases could be prevented through healthier dietary choices and lifestyle modifications (World Health Organization, 2019). This essay aims to...
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Abstract Cancer is a frightful disease and represents one of the biggest health-care issues for the human race and demands a proactive strategy for cure. Exploration of natural product containing anticancer agent provide a promising line for research on cancer. Moringa plant (Moringa oleifera) is one of the medicinal plants used in traditional medicine for the treatment of cancer. Several...
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Popeye domain-containing (POPDC) proteins are effector proteins that bind to cAMP to create a second messenger response that can influence the behaviour of cancer cells (Amunjela & Tucker, 2016). There are three different genes POPDC1, POPDC2 and POPDC3 that encode these proteins, however only POPDC1 and POPDC3 have been related to cancer cell behaviour. POPDC1 and POPDC3 are organised in...
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In cancer research, viability tests are immensely significant. These tests are used to observe the characteristics of different kinds of cancer. In drug development, viability of hostile cells are tested against chemical substances to evaluate the potential of those substances in pharmaceutical use. Additionally, the adequate dosage for those drugs are also studied in vitro. Established in 1977 from a...
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In recent years, AI has gradually entered the medical field. Artificial intelligence continues to break through the sensitivity and specificity of machine-assisted diagnosis at the 'digital' level, and exerts its value in multiple scenarios. However, many products are still far from large-scale clinical applications, and it is not easy to obtain the approval of clinicians. For the big names in...
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Introduction Lung cancer remains one of the most prevalent and deadly forms of cancer worldwide, with significant impacts on patients, families, and healthcare systems. According to the World Health Organization, lung cancer accounts for approximately 2.2 million new cases annually, representing a substantial public health challenge. This essay explores the various dimensions of lung cancer, including its symptoms, diagnostic processes,...
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Breast Cancer is a common cancer in Hong Kong. It can be divided into invasive and non-invasive (Akram, 2017). Breast cancer does not only exist in females, but also exist in males. According to the Centre for Health Protection, there are total 4108 females and 15 males who are diagnosed in breast cancer respectively in 2016. The morbidly rate in...
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ABSTRACT Rise in deaths due to prostate and breast cancer are expected to continue in future. These diseases are the most common types of cancer for men and women across the globe. Machine Learning can be used to drop the number of deaths by these diseases with early detection. One of them is the classification of data of prostate cancer...
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Introduction This essay will seek to discuss the role of androgen receptor therapy in advanced prostate cancer. Prostate cancer and the androgen receptor (AR) will be discussed, namely the origins of androgen receptor targeted therapy, its development and role in treatment of advanced prostate cancer today, and the future of targeted therapy. Androgen receptor targeted therapy is utilised in advanced...
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Meg, age 50, currently on post-menopausal, was diagnosed with Invasive Ductal Carcinoma (IDC), also known as one of the most common forms of breast cancer (âInvasive Ductal Carcinoma,â n.d.). The first sign of cancer was detected through a mammogram, followed by a physical examination and later confirmed by an ultrasound and biopsy. Three tumours/ lymph nodes were discovered. After surgery,...
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What is lung cancer? Lung cancer has become the most prevalent and threatening cancer worldwide. Parallel to most malignancies, lung cancer is composed of sub-populations of cells with distinct molecular features, resulting in intra-tumoral heterogeneity (Herbst, et.al, 2018). There are two types of lung cancer; small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) (Molina, et.al, 2008). NSCLC...
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Research has shown that one of the main biological factors for an individual for the development of skin cancer is that of their heritage, being of European decent. The level of pigmentation in a person's skin has a direct affect on the possibility of being diagnosed with skin cancer . Many Australians still hold the belief that having a tan...
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